Associate Director, Biotherapeutic Production and Characterization Job at Generate Biomedicines, Somerville, MA

  • Generate Biomedicines
  • Somerville, MA

Job Description

Generate Biomedicines seeks an Associate Director to lead biotherapeutic production and characterization operations. The role oversees protein expression, purification, and characterization across multiple systems while driving innovation in complex protein production and advancing automation and data practices.

Responsibilities

  • Oversee end-to-end protein production workflows including expression, purification, and characterization across multiple systems
  • Drive innovation for difficult-to-produce proteins through construct optimization and enabling technologies
  • Establish fit-for-purpose production standards and quality metrics for diverse protein attributes
  • Lead team planning, resource allocation, and external partner management across internal and outsourced activities
  • Lead adoption of automation and AI/ML-enabled tools while advancing operational excellence and continuous improvement

Requirements

  • Deep expertise in protein production across mammalian, bacterial, and cell-free expression systems
  • Strong background in protein purification, characterization, and quality control methods
  • Experience with construct design, optimization, and alternative expression modalities
  • Demonstrated ability to manage cross-functional teams and external partnerships
  • Knowledge of automation, data practices, and emerging AI/ML tools in biomanufacturing
  • Track record leading scientific strategy and portfolio prioritization in biotech

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